Publication
Title
Does immune response cause oxidative stress in birds? A meta-analysis
Author
Abstract
In recent years ecological research has focused on the relevance of antioxidants and oxidative stress in the evolution of life-history strategies and physiological trade-off in birds. Some studies sought to evaluate whether a consequence of immune response is oxidative stress. In a meta-analysis of 16 studies of ten species of birds including 49 estimates of effect size from experimental studies, we show that induction of an immune response in a diverse group of bird species may determine oxidative stress (variance explained: 4.1%), but, most notably, may determine changes in oxidative stress markers (variance explained: 15.0%). These conclusions were robust to control for sampling effort and publication bias. Finally, this finding suggests that (1) oxidative stress may be a physiological cost associated with the immune response and (2) an important role of antioxidants in birds is to control the potentially negative effects of such oxidative stress to prevent immuno-pathological damage to host tissues.
Language
English
Source (journal)
Comparative biochemistry and physiology : A : molecular & integrative physiology. - London
Publication
London : 2009
ISSN
1095-6433
Volume/pages
153:3(2009), p. 339-344
ISI
000266686700015
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 09.10.2015
Last edited 22.11.2017