Publication
Title
Whole genome sequencing of childrens DNA for research : points to consider
Author
Abstract
Techniques to sequence the entire exome or even genome of an individual are evolving rapidly. Experts believe that in the future it will be possible to sequence the whole genome of an individual for a thousand dollars or less [1]. The advent of cost-effective sequencing techniques opens many possibilities for genetic diagnostics and screening. Furthermore, genetic research will also benefit greatly [2]. For example, research on the genetic component of Autism Spectrum Disorder could take a huge leap forward, as the genes contributing to this disorder are believed to be located throughout the genome [3]. Genetic research on extracted DNA from children has proven to be necessary and fruitful. Such research can focus on specific childhood diseases but can also take the form of longitudinal cohort studies, where children are followed for several years to match genotypical and phenotypical data. The ethical issues raised by the participation of children in genetic research are not analogous to those raised by adult participation, nor do they correspond completely to those raised by the participation of children in clinical trials. These issues include questions about risks and benefits, the scope of parental consent and the return of individual research results.
Language
English
Source (journal)
Journal of clinical research & bioethics
Publication
2011
Volume/pages
2:7(2011), p. 106e
Full text (Publishers DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Publication type
Subject
External links
Record
Identification
Creation 12.10.2015
Last edited 21.11.2016