Title
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Rapid low dose electron tomography using a direct electron detection camera
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Author
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Abstract
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We demonstrate the ability to record a tomographic tilt series containing 3487 images in only 3.5 s by using a direct electron detector in a transmission electron microscope. The electron dose is lower by at least one order of magnitude when compared with that used to record a conventional tilt series of fewer than 100 images in 15-60 minutes and the overall signal-to-noise ratio is greater than 4. Our results, which are illustrated for an inorganic nanotube, are important for ultra-low-dose electron tomography of electron-beam-sensitive specimens and real-time dynamic electron tomography of nanoscale objects with sub-ms temporal resolution. |
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Language
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English
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Source (journal)
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Scientific reports. - London, 2011, currens
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Publication
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London
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Nature Publishing Group
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2015
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ISSN
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2045-2322
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DOI
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10.1038/SREP14516
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Volume/pages
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5
(2015)
, 5 p.
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Article Reference
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14516
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ISI
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000362178900001
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Pubmed ID
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26434767
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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