Title
COLOMBOS v3.0 : leveraging gene expression compendia for cross-species analyses COLOMBOS v3.0 : leveraging gene expression compendia for cross-species analyses
Author
Faculty/Department
Faculty of Sciences. Mathematics and Computer Science
Publication type
article
Publication
London ,
Subject
Chemistry
Biology
Human medicine
Computer. Automation
Source (journal)
Nucleic acids research. - London
Volume/pages
44(2016) :D1 , p. D620-D623
ISSN
0305-1048
ISI
000371261700087
Carrier
E
Target language
Dutch (dut)
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
COLOMBOS is a database that integrates publicly available transcriptomics data for several prokaryotic model organisms. Compared to the previous version it has more than doubled in size, both in terms of species and data available. The manually curated condition annotation has been overhauled as well, giving more complete information about samples' experimental conditions and their differences. Functionality-wise cross-species analyses now enable users to analyse expression data for all species simultaneously, and identify candidate genes with evolutionary conserved expression behaviour. All the expression-based query tools have undergone a substantial improvement, overcoming the limit of enforced co-expression data retrieval and instead enabling the return of more complex patterns of expression behaviour. COLOMBOS is freely available through a web application at http://colombos.net/. The complete database is also accessible via REST API or downloadable as tab-delimited text files.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/bc87f6/128945.pdf
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