Title
SFINX : straightforward filtering index for affinity purificationmass spectrometry data analysis SFINX : straightforward filtering index for affinity purificationmass spectrometry data analysis
Author
Faculty/Department
Faculty of Sciences. Biology
Faculty of Sciences. Chemistry
Faculty of Sciences. Mathematics and Computer Science
Publication type
article
Publication
Subject
Chemistry
Biology
Computer. Automation
Source (journal)
Journal of proteome research
Volume/pages
15(2016) :1 , p. 332-338
ISSN
1535-3893
ISI
000367706000027
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Affinity purificationmass spectrometry is one of the most common techniques for the analysis of proteinprotein interactions, but inferring bona fide interactions from the resulting data sets remains notoriously difficult. We introduce SFINX, a Straightforward Filtering INdeX that identifies true-positive protein interactions in a fast, user-friendly, and highly accurate way. SFINX outperforms alternative techniques on two benchmark data sets and is available via the Web interface at http://sfinx.ugent.be/.
E-info
https://repository.uantwerpen.be/docman/iruaauth/d903b9/129796.pdf
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