Publication
Title
Development of composite outcomes for individual patient data (IPD) meta-analysis on the effects of diet and lifestyle in pregnancy: a Delphi survey
Author
Institution/Organisation
International Weight Management in Pregnancy (iWIP) Collaborative Group
Abstract
Objective To develop maternal, fetal, and neonatal composite outcomes relevant to the evaluation of diet and lifestyle interventions in pregnancy by individual patient data (IPD) meta-analysis. Design Delphi survey. Setting The International Weight Management in Pregnancy (iWIP) collaborative network. Sample Twenty-six researchers from the iWIP collaborative network from 11 countries. Methods A two-generational Delphi survey involving members of the iWIP collaborative network (26 members in 11 countries) was undertaken to prioritise the individual outcomes for their importance in clinical care. The final components of the composite outcomes were identified using pre-specified criteria. Main outcome measures Composite outcomes considered to be important for the evaluation of the effect of diet and lifestyle in pregnancy. Results Of the 36 maternal outcomes, nine were prioritised and the following were included in the final composite: pre-eclampsia or pregnancy-induced hypertension, gestational diabetes mellitus (GDM), elective or emergency caesarean section, and preterm delivery. Of the 27 fetal and neonatal outcomes, nine were further evaluated, with the final composite consisting of intrauterine death, small for gestational age, large for gestational age, and admission to a neonatal intensive care unit (NICU). Conclusions Our work has identified the components of maternal, fetal, and neonatal composite outcomes required for the assessment of diet and lifestyle interventions in pregnancy by IPD meta-analysis.
Language
English
Source (journal)
BJOG: an international journal of obstetrics and gynaecology. - London
Publication
London : 2016
ISSN
1470-0328 [print]
1471-0528 [online]
Volume/pages
123:2(2016), p. 190-198
ISI
000367474700009
Full text (Publisher's DOI)
Full text (open access)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Project info
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 06.01.2016
Last edited 23.11.2017
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