Title
Genetic Creutzfeldt-Jakob disease mimicking chronic inflammatory demyelinating polyneuropathy Genetic Creutzfeldt-Jakob disease mimicking chronic inflammatory demyelinating polyneuropathy
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Subject
Biology
Human medicine
Source (journal)
Neurology Neuroimmunology & Neuroinflammation
Volume/pages
2(2015) :6 , p. 1-2
ISSN
2332-7812
Article Reference
e173
Carrier
E-only publicatie
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Creutzfeldt-Jakob disease (CJD) is a relentlessly progressive neurodegenerative disorder, belonging to the transmissible spongiform encephalopathies. It is characterized by the deposition of the abnormal isoform of the prion protein (PrPsc), causing spongiform neurodegeneration. The disease is classically known to mainly affect the gray matter of the CNS. However, involvement of the peripheral nervous system (PNS) has been described.1,3 Herein, we describe a patient with genetic CJD, in whom the disease presentation was a demyelinating neuropathy reminiscent of chronic inflammatory demyelinating polyneuropathy (CIDP).
E-info
https://repository.uantwerpen.be/docman/iruaauth/f589ed/130648.pdf
Handle