Title
Clinical recommendations for defining platinum unsuitable head and neck cancer patient populations on chemoradiotherapy : a literature reviewClinical recommendations for defining platinum unsuitable head and neck cancer patient populations on chemoradiotherapy : a literature review
Author
Faculty/Department
Faculty of Medicine and Health Sciences
Research group
Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO)
Publication type
article
Publication
Amsterdam :Elsevier science bv,
Subject
Human medicine
Source (journal)
Oral oncology. - Oxford, 1997, currens
Volume/pages
53(2016), p. 10-16
ISSN
1368-8375
ISI
000367523100002
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
Toxicities resulting from platinum based chemotherapy in head and neck cancer is a cause for much concern. There is a lack of clinical criteria for defining these patient populations, which has posed serious problems associated with increased morbidity and consequently an adverse effect on patients' quality of life. In addition, there is a lack of consensus on clinical criteria for defining such patient populations, who may be unsuitable for concurrent chemoradiotherapy. A group of experts in the field of head and neck cancer from the Asia Pacific Region convened in August 2014 in Korea to discuss the development of a set of clinical criteria in order to fill the knowledge gap and provide a reference tool for head and neck oncologists. This paper reports the final output from this meeting and the accompanying literature review, with the aim of aiding clinical decision making with the help of some clinical criteria to identify platinum unsuitable patient populations in head and neck cancer management. Some alternative treatment options are also discussed in this paper. (C) 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.
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Full text (open access)
https://repository.uantwerpen.be/docman/irua/454b03/131065.pdf
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