Publication
Title
Antimicrobial assessment of resins from Calophyllum Antillanum and Calophyllum Inophyllum
Author
Abstract
The Calophyllum genus is well-known for its antimicrobial and cytotoxic activities, and therefore, we analyzed these biological activities for resins of Calophyllum antillanum and Calophyllum inophyllum growing in Cuba. C. antillanum resins showed a potent activity against Plasmodium falciparum (IC50 = 0.3 +/- 0.1 mu g/mL), while its cytotoxicity against MRC-5 cells was much lower (IC50 = 21.6 +/- 1.1 mu g/mL). In contrary, the resin of C. inophyllum showed an unspecific activity. The presence of apetalic acid, isoapetalic acid, calolongic acid, pinetoric acid I, pinetoric acid II, isocalolongic acid, pinetoric acid III, and isopinetoric acid III in C. antillanum resins was also confirmed. These results demonstrated for the first time the potential activity of C. antillanum resins against P. falciparum. Copyright (C) 2015 John Wiley & Sons, Ltd.
Language
English
Source (journal)
Phytotherapy research. - London
Publication
London : 2015
ISSN
0951-418X
Volume/pages
29:12(2015), p. 1991-1994
ISI
000367905400019
Full text (Publishers DOI)
Full text (publishers version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 16.02.2016
Last edited 17.05.2017
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