Publication
Title
Distribution of the crystalline lens power in vivo as a function of age
Author
Institution/Organisation
EVICR Net
Project Gullstrand Study Grp
Abstract
PURPOSE. To observe the age-related changes in crystalline lens power in vivo in a noncataractous European population. METHODS. Data were obtained though Project Gullstrand, a multicenter population study with data from healthy phakic subjects between 20 and 85 years old. One randomly selected eye per subject was used. Lens power was calculated using the modified Bennett-Rabbetts method, using biometry data from an autorefractometer, Oculus Pentacam, and Haag-Streit Lenstar. RESULTS. The study included 1069 Caucasian subjects (490 men, 579 women) with a mean age of 44.2 +/- 14.2 years and mean lens power of 24.96 +/- 2.18 diopters (D). The average lens power showed a statistically significant decrease as a function of age, with a steeper rate of decrease after the age of 55. The highest crystalline lens power was found in emmetropic eyes and eyes with a short axial length. The correlation of lens power with different refractive components was statistically significant for axial length (r = -0.523, P < 0.01) and anterior chamber depth (r = -0.161, P < 0.01), but not for spherical equivalent and corneal power (P > 0.05). CONCLUSIONS. This in vivo study showed a monotonous decrease in crystalline lens power with age, with a steeper decline after 55 years. While this finding fundamentally concurs with previous in vivo studies, it is at odds with studies performed on donor eyes that reported lens power increases after the age of 55.
Language
English
Source (journal)
Investigative ophthalmology and visual science. - St. Louis, Mo.
Publication
St. Louis, Mo. : 2015
ISSN
0146-0404
Volume/pages
56:12(2015), p. 7029-7035
ISI
000368238200004
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 16.02.2016
Last edited 20.06.2017
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