Publication
Title
Colistin-resistant Acinetobacter baumannii clinical strains deficient in biofilm formation
Author
Abstract
In two pairs of clinical colistin-susceptible/colistin-resistant (ColS/ColR) Acinetobacter baumannii, ColR strains showed significantly decreased biofilm formation in static and dynamic assays (P<0.001) and lower relative fitness (P<0.05) compared with ColS. Whole genome sequencing comparison of strain pairs identified in one ColR strain a *241K change in LpsB (involved in LPS synthesis) and in the other, a frameshift mutation in CarO and loss of a 47,969 bp element containing multiple genes associated with biofilm production.
Language
English
Source (journal)
Antimicrobial agents and chemotherapy. - Washington, D.C.
Publication
Washington, D.C. : 2016
ISSN
0066-4804
Volume/pages
60:3(2016), p. 1892-1895
ISI
000376490800093
Full text (Publishers DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 22.02.2016
Last edited 17.05.2017
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