Publication
Title
Childhood obesity related endothelial dysfunction : an update on pathophysiological mechanisms and diagnostic advancements
Author
Abstract
Childhood obesity jeopardizes a healthy future for our societys children as it is associated with increased cardiovascular morbidity and mortality later on in life. Endothelial dysfunction, the first step in the development of atherosclerosis, is already present in obese children and may well represent a targetable risk factor. Technological advancements in recent years have facilitated non-invasive measurements of endothelial homeostasis in children. Thereby this topic ultimately starts to get the attention it deserves. In this paper, we aim to summarize the latest insights on endothelial dysfunction in childhood obesity. We discuss methodological advancements in peripheral endothelial function measurement and newly identified diagnostic markers of vascular homeostasis. Finally, future challenges and perspectives are set forth on how to efficiently tackle the catastrophic rise in cardiovascular morbidity and mortality that will be inflicted on obese children if they are not treated optimally.
Language
English
Source (journal)
Pediatric research. - Basel
Publication
Basel : 2016
ISSN
0031-3998
Volume/pages
79:6(2016), p. 831-837
ISI
000377481100004
Full text (Publishers DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 26.02.2016
Last edited 06.05.2017
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