Title
Co-exposure of ELF-magnetic fields and chemical mutagens : an investigation of genotoxicity with the SOS-based VITOTOX test in Salmonella typhimurium
Author
Faculty/Department
Faculty of Pharmaceutical, Biomedical and Veterinary Sciences . Biomedical Sciences
Publication type
article
Publication
Amsterdam ,
Subject
Biology
Pharmacology. Therapy
Human medicine
Engineering sciences. Technology
Source (journal)
Mutation research. Genetic toxicology and environmental mutagenesis. - Amsterdam
Volume/pages
795(2016) , p. 31-35
ISSN
1383-5718
ISI
000369454100003
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
It is believed that extreme low frequency magnetic fields (ELF-MF) are not mutagenic, at least at exposure levels below 100 mu T. Synergistic or co-operative effects with environmental mutagens remain possible yet. We therefore investigated the effects of ELF-MF in conjunction with 4 different well known chemical mutagens having different modes of action. For this purpose the bacterial Vitotox test was used. Our study confirmed previous results which showed that a 100 mu T magnetic field (50 Hz) does not damage DNA and hence is not mutagenic in this assay and that there was also no influence on the DNA damaging capacity of the used mutagens. (C) 2015 Elsevier B.V. All rights reserved.
E-info
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https://repository.uantwerpen.be/docman/iruaauth/4c0a64/131634.pdf
Handle