Publication
Title
Fast and reliable quantitative peptidomics with labelpepmatch
Author
Abstract
The use of stable isotope tags in quantitative peptidomics offers many advantages, but the laborious identification of matching sets of labeled peptide peaks is still a major bottleneck. Here we present labelpepmatch, an R package for fast and straightforward analysis of LC MS spectra of labeled peptides. This open-source tool offers fast and accurate identification of peak pairs alongside an appropriate framework for statistical inference on quantitative peptidomics data, based on techniques from other-omics disciplines. A relevant case study on the desert locust Schistocerca gregaria proves our pipeline to be a reliable tool for quick but thorough explorative analyses.
Language
English
Source (journal)
Journal of proteome research
Publication
2016
ISSN
1535-3893
Volume/pages
15:3(2016), p. 1080-1089
ISI
000371754100040
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 08.04.2016
Last edited 09.06.2017
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