Title
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Neuroprotection in acute brain injury : an up-to-date review
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Author
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Abstract
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Neuroprotective strategies that limit secondary tissue loss and/or improve functional outcomes have been identified in multiple animal models of ischemic, hemorrhagic, traumatic and nontraumatic cerebral lesions. However, use of these potential interventions in human randomized controlled studies has generally given disappointing results. In this paper, we summarize the current status in terms of neuroprotective strategies, both in the immediate and later stages of acute brain injury in adults. We also review potential new strategies and highlight areas for future research. |
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Language
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English
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Source (journal)
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Critical care. - London
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Publication
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London
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2015
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ISSN
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1364-8535
1466-609X
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DOI
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10.1186/S13054-015-0887-8
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Volume/pages
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19
(2015)
, 11 p.
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Article Reference
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UNSP 186
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ISI
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000353201000001
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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