Title
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Prevalence of HBV and HCV among outpatients in the Plovdiv region of Bulgaria, 2010-2011
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Author
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Abstract
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Viral hepatitis, particularly hepatitis B and C, are diseases with worldwide distribution that present a significant public health problem. Seroprevalence studies allow assessment of the extent of the disease burden, the identification of populations at risk and the monitoring trends over time. A multi-center seroprevalence study, carried out in Bulgaria (covering the five largest cities - Sofia, Plovdiv, Varna, Pleven, and Stara Zagora) in 1999-2000 estimated a crude seroprevalence rate of 3.9% for HBsAg and 1.3% for anti-HCV. A decade later, comparable rates were observed in a study including 865 outpatients consulting a clinical laboratory in Plovdiv, the second largest administrative region in Bulgaria. The crude seroprevalence rate measured for hepatitis B (HBsAg) was 3.9%. The HBsAg prevalence rate in individuals 19 years of age (targeted by vaccination) was significantly lower compared to the rate in adults 20 years of age -1% versus 4.8%. The lack of dynamics in the overall level of HBsAg carriers is likely related to the excessively low hepatitis B vaccine coverage in individuals, born before the introduction of the universal vaccination of newborns in August 1991. Anti-HCV antibodies were detected in 0.7% of the subjects. J. Med. Virol. 87:401-406, 2015. (c) 2014 Wiley Periodicals, Inc. |
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Language
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English
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Source (journal)
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Journal of medical virology. - New York, N.Y.
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Publication
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New York, N.Y.
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2015
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ISSN
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0146-6615
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DOI
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10.1002/JMV.24065
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Volume/pages
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87
:3
(2015)
, p. 401-406
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ISI
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000348566300006
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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