Title
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Unraveling the triterpenoid saponin biosynthesis of the African shrub **Maesa lanceolata**
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Author
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Abstract
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Maesasaponins produced by the African shrub Maesa lanceolata are oleanane-type saponins with diverse biological activities. Through a combination of transcript profiling of methyl jasmonate-elicited M. lanceolata shoot cultures, functional analysis in transgenic M. lanceolata plants and the heterologous hosts Medicago truncatula and Saccharomyces cerevisiae, we identified three maesaponin biosynthesis genes. These include a beta-amyrin synthase and two cytochrome P450s, CYP716A75 and CYP87D16, which catalyze the C-28 and C-16 alpha oxidations of b-amyrin, respectively. |
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Language
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English
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Source (journal)
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Molecular plant. - -
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Publication
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2015
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ISSN
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1674-2052
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DOI
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10.1016/J.MOLP.2014.11.004
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Volume/pages
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8
:1
(2015)
, p. 122-135
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ISI
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000350812900012
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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