Publication
Title
Basilar membrane and reticular lamina motion in a multi-scale finite element model of the mouse cochlea
Author
Abstract
A multi-scale finite element (FE) model of the mouse cochlea, based on its anatomy and material properties is presented. The important feature in the model is a lattice of 400 Y-shaped structures in the longitudinal direction, each formed by Deiters cells, phalangeal processes and outer hair cells (OHC). OHC somatic motility is modeled by an expansion force proportional to the shear on the stereocilia, which in turn is proportional to the pressure difference between the scala vestibule and scala tympani. Basilar membrane (BM) and reticular lamina (RL) velocity compare qualitatively very well with recent in vivo measurements in guinea pig [2]. Compared to the BM, the RL is shown to have higher amplification and a shift to higher frequencies. This comes naturally from the realistic Y-shaped cell organization without tectorial membrane tuning.
Language
English
Source (journal)
AIP conference proceedings / American Institute of Physics. - New York
Source (book)
12th International Workshop on the Mechanics of Hearing, JUN 23-29, 2014, Cape Sounio, GREECE
Publication
Melville : Amer inst physics , 2015
ISSN
0094-243X
ISBN
978-0-7354-1350-4
978-0-7354-1350-4
DOI
10.1063/1.4939351
Volume/pages
1703 (2015) , 5 p.
Article Reference
050006
ISI
000372065400038
Medium
E-only publicatie
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 10.05.2016
Last edited 09.10.2023
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