Title
Basilar membrane and reticular lamina motion in a multi-scale finite element model of the mouse cochlea
Author
Faculty/Department
Faculty of Sciences. Physics
Publication type
conferenceObject
Publication
Melville :Amer inst physics ,
Subject
Physics
Chemistry
Biology
Human medicine
Source (journal)
AIP conference proceedings / American Institute of Physics. - New York
Source (book)
12th International Workshop on the Mechanics of Hearing, JUN 23-29, 2014, Cape Sounio, GREECE
Volume/pages
1703(2015) , 5 p.
ISSN
0094-243X
0094-243X
Article Reference
050006
ISBN
978-0-7354-1350-4
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
A multi-scale finite element (FE) model of the mouse cochlea, based on its anatomy and material properties is presented. The important feature in the model is a lattice of 400 Y-shaped structures in the longitudinal direction, each formed by Deiters cells, phalangeal processes and outer hair cells (OHC). OHC somatic motility is modeled by an expansion force proportional to the shear on the stereocilia, which in turn is proportional to the pressure difference between the scala vestibule and scala tympani. Basilar membrane (BM) and reticular lamina (RL) velocity compare qualitatively very well with recent in vivo measurements in guinea pig [2]. Compared to the BM, the RL is shown to have higher amplification and a shift to higher frequencies. This comes naturally from the realistic Y-shaped cell organization without tectorial membrane tuning.
E-info
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372065400038&DestLinkType=RelatedRecords&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372065400038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=ef845e08c439e550330acc77c7d2d848
Full text (open access)
https://repository.uantwerpen.be/docman/irua/13e0f4/133181.pdf
Handle