Publication
Title
Alice in microbes' land : adaptations and counter-adaptations of vector-borne parasitic protozoa and their hosts
Author
Abstract
In the present review, we aim to provide a general introduction to different facets of the arms race between pathogens and their hosts/environment, emphasizing its evolutionary aspects. We focus on vector-borne parasitic protozoa, which have to adapt to both invertebrate and vertebrate hosts. Using Leishmania, Trypanosoma and Plasmodium as main models, we review successively (i) the adaptations and counter-adaptations of parasites and their invertebrate host, (ii) the adaptations and counter-adaptations of parasites and their vertebrate host and (iii) the impact of human interventions (chemotherapy, vaccination, vector control and environmental changes) on these adaptations. We conclude by discussing the practical impact this knowledge can have on translational research and public health.
Language
English
Source (journal)
FEMS microbiology: reviews / Federation of European Microbiological Societies. - Amsterdam
Publication
Amsterdam : 2016
ISSN
0168-6445
Volume/pages
(2016), p. 1-22
ISI
000385138200006
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 15.07.2016
Last edited 19.11.2017
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