Publication
Title
Absolute configuration of the antimalarial erythro-mefloquine Vibrational Circular Dichroism and X-ray diffraction studies of mefloquine and its thiourea derivative
Author
Abstract
The long-standing discussion of the absolute configuration of erythro-mefloquine is revisited, showcasing the strength of a combination of experimental and calculated Vibrational Circular Dichroism spectroscopy. The resulting assignment of one of the most important antimalarials is subsequently confirmed by Electronic Circular Dichroism spectroscopy and X-ray diffraction-based structure elucidation of thiourea derivates, adding to the amount of evidence on the absolute configuration that had long remained a matter of debate.
Language
English
Source (journal)
RSC advances
Publication
2016
ISSN
2046-2069
Volume/pages
6:85(2016), p. 81461-81465
ISI
000382776000001
Full text (Publishers DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 26.08.2016
Last edited 08.05.2017
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