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Title
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Amine activation : synthesis of N‑(hetero)arylamides from isothioureas and carboxylic acids
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Author
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Abstract
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| A novel method for N-(hetero)arylamide synthesis based on rarely explored amine activation, rather than classical acid activation, is reported. The activated amines are easily prepared using a three-component reaction with commercial reagents. The new method shows a broad scope including challenging amides not (efficiently) accessible via classical protocols. |
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Language
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English
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Source (journal)
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Organic letters / American Chemical Society. - Washington, D.C.
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Publication
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Washington, D.C.
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2016
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ISSN
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1523-7060
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DOI
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10.1021/ACS.ORGLETT.6B02247
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Volume/pages
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18
:18
(2016)
, p. 4602-4605
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ISI
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000383640600040
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Pubmed ID
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27570902
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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