Publication
Title
Amine activation : synthesis of N‑(hetero)arylamides from isothioureas and carboxylic acids
Author
Abstract
A novel method for N-(hetero)arylamide synthesis based on rarely explored amine activation, rather than classical acid activation, is reported. The activated amines are easily prepared using a three-component reaction with commercial reagents. The new method shows a broad scope including challenging amides not (efficiently) accessible via classical protocols.
Language
English
Source (journal)
Organic letters / American Chemical Society. - Washington, D.C.
Publication
Washington, D.C. : 2016
ISSN
1523-7060
Volume/pages
18:18(2016), p. 4602-4605
ISI
000383640600040
Full text (Publisher's DOI)
Full text (open access)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
[E?say:metaLocaldata.cgzprojectinf]
Chemical Manufacturing Methods for the 21st Century Pharmaceuticals Industries (CHEM21).
Sustainable Synthesis of Amides (SUSAMIDE).
Transition metal-catalyzed amide cleavage.
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 26.08.2016
Last edited 28.08.2017
To cite this reference