Publication
Title
Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016
Author
Abstract
We identified a novel plasmid-mediated colistin-resistance gene in porcine and bovine colistin-resistant Escherichia coli that did not contain mcr-1. The gene, termed mcr-2, a 1,617 bp phosphoethanolamine transferase harboured on an IncX4 plasmid, has 76.7% nucleotide identity to mcr-1. Prevalence of mcr-2 in porcine colistin-resistant E. coli (11/53) in Belgium was higher than that of mcr-1 (7/53). These data call for an immediate introduction of mcr-2 screening in ongoing molecular epidemiological surveillance of colistin-resistant Gram-negative pathogens.
Language
English
Source (journal)
Eurosurveillance : European communicable disease bulletin / European Communities. Commission; Communautés européennes. Commission. - Saint-Maurice, 1995, currens
Publication
Saint-Maurice : 2016
ISSN
1025-496X [print]
1560-7917 [online]
DOI
10.2807/1560-7917.ES.2016.21.27.30280
Volume/pages
21 :27 (2016) , p. 8-13
Article Reference
30280
ISI
000379696400002
Medium
E-only publicatie
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Project info
COllaborative Management Platform for detection and Analyses of (Re-)emerging and foodborne outbreaks in Europe (COMPARE)
Mechanistic insights on colistin resistance in pathogenic Escherichia coli and Klebsiella species.
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 02.09.2016
Last edited 09.10.2023
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