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Title
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Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016
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Author
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Abstract
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| We identified a novel plasmid-mediated colistin-resistance gene in porcine and bovine colistin-resistant Escherichia coli that did not contain mcr-1. The gene, termed mcr-2, a 1,617 bp phosphoethanolamine transferase harboured on an IncX4 plasmid, has 76.7% nucleotide identity to mcr-1. Prevalence of mcr-2 in porcine colistin-resistant E. coli (11/53) in Belgium was higher than that of mcr-1 (7/53). These data call for an immediate introduction of mcr-2 screening in ongoing molecular epidemiological surveillance of colistin-resistant Gram-negative pathogens. |
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Language
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English
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Source (journal)
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Eurosurveillance : European communicable disease bulletin / European Communities. Commission; Communautés européennes. Commission. - Saint-Maurice, 1995, currens
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Publication
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Saint-Maurice
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2016
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ISSN
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1025-496X
[print]
1560-7917
[online]
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Volume/pages
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21
:27
(2016)
, p. 8-13
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Article Reference
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30280
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ISI
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000379696400002
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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