Publication
Title
Molecular profiles to biology and pathways: a systems biology approach
Author
Abstract
Interpreting molecular profiles in a biological context requires specialized analysis strategies. Initially, lists of relevant genes were screened to identify enriched concepts associated with pathways or specific molecular processes. However, the shortcoming of interpreting gene lists by using predefined sets of genes has resulted in the development of novel methods that heavily rely on network-based concepts. These algorithms have the advantage that they allow a more holistic view of the signaling properties of the condition under study as well as that they are suitable for integrating different data types like gene expression, gene mutation, and even histological parameters.
Language
English
Source (journal)
Chinese Journal of Cancer
Publication
Guangzhou : Sun yat sen univ med sci who, 2016
ISSN
1000-467X
Volume/pages
35(2016), 3 p.
Article Reference
53
ISI
000380164500001
Medium
E-only publicatie
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 02.09.2016
Last edited 09.06.2017
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