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Title
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Kidney activity increases in copper exposed goldfish (**Carassius auratus auratus**)
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Author
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Abstract
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| In the present study, the effect of copper was examined in the common goldfish (Carassius auratus auratus). Fish were fasted and exposed to either a high (0.84 μM), a low (0.34 μM) or a control copper concentration (0.05 μM) for 1 and 7 days. Swimming performance was not affected by either fasting or copper exposure. Food deprivation alone had no effect on ionoregulation, but low plasma osmolality levels and plasma Na+ were noticed in fasted fish exposed to Cu for 7 days. Both gill Na+/K+-ATPase and H+-ATPase activities were undisturbed, while both kidney ATPase activities were up-regulated when challenged with the high Cu levels. Up-regulated kidney ATPase activities likely acted as compensatory strategy to enhance Na+ reabsorption. However, this up-regulation was not sufficient to restore Na+ to control levels in the highest exposure group. |
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Language
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English
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Source (journal)
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Comparative biochemistry and physiology : C : toxicology & pharmacology. - Oxford, 2000, currens
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Publication
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Oxford
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2016
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ISSN
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1532-0456
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DOI
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10.1016/J.CBPC.2016.08.003
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Volume/pages
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190
(2016)
, p. 32-37
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ISI
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000388549700005
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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