Kidney activity increases in copper exposed goldfish (**Carassius auratus auratus**)
Faculty of Sciences. Biology
Comparative biochemistry and physiology : C : toxicology & pharmacology. - Oxford, 2000, currens
, p. 32-37
University of Antwerp
In the present study, the effect of copper was examined in the common goldfish (Carassius auratus auratus). Fish were fasted and exposed to either a high (0.84 μM), a low (0.34 μM) or a control copper concentration (0.05 μM) for 1 and 7 days. Swimming performance was not affected by either fasting or copper exposure. Food deprivation alone had no effect on ionoregulation, but low plasma osmolality levels and plasma Na+ were noticed in fasted fish exposed to Cu for 7 days. Both gill Na+/K+-ATPase and H+-ATPase activities were undisturbed, while both kidney ATPase activities were up-regulated when challenged with the high Cu levels. Up-regulated kidney ATPase activities likely acted as compensatory strategy to enhance Na+ reabsorption. However, this up-regulation was not sufficient to restore Na+ to control levels in the highest exposure group.