Title
Kidney activity increases in copper exposed goldfish (**Carassius auratus auratus**) Kidney activity increases in copper exposed goldfish (**Carassius auratus auratus**)
Author
Faculty/Department
Faculty of Sciences. Biology
Publication type
article
Publication
Oxford ,
Subject
Biology
Source (journal)
Comparative biochemistry and physiology : C : toxicology & pharmacology. - Oxford, 2000, currens
Volume/pages
190(2016) , p. 32-37
ISSN
1532-0456
Carrier
E
Target language
English (eng)
Full text (Publishers DOI)
Affiliation
University of Antwerp
Abstract
In the present study, the effect of copper was examined in the common goldfish (Carassius auratus auratus). Fish were fasted and exposed to either a high (0.84 μM), a low (0.34 μM) or a control copper concentration (0.05 μM) for 1 and 7 days. Swimming performance was not affected by either fasting or copper exposure. Food deprivation alone had no effect on ionoregulation, but low plasma osmolality levels and plasma Na+ were noticed in fasted fish exposed to Cu for 7 days. Both gill Na+/K+-ATPase and H+-ATPase activities were undisturbed, while both kidney ATPase activities were up-regulated when challenged with the high Cu levels. Up-regulated kidney ATPase activities likely acted as compensatory strategy to enhance Na+ reabsorption. However, this up-regulation was not sufficient to restore Na+ to control levels in the highest exposure group.
Full text (open access)
https://repository.uantwerpen.be/docman/irua/71a2a5/135824.pdf
E-info
https://repository.uantwerpen.be/docman/iruaauth/e8bf5c/135824.pdf
Handle