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Title
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EEG dominant frequency peak differentiates between Alzheimers disease and frontotemporal lobar degeneration
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Author
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Abstract
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| Abstract. We investigated the power of EEG as biomarker in differential diagnosis of Alzheimers disease (AD) and frontotemporal lobar degeneration (FTLD). EEG was recorded from 106 patients with AD or FTLD, of which 37 had a definite diagnosis, and 40 controls. Dominant frequency peaks were extracted for all 19 channels, for each subject. The average frequency of the largest dominant frequency peaks (maxpeak) was significantly lower in AD than FTLD patients and controls. Based on ROC analysis, classification could be made with diagnostic accuracy of 78.9%. Our findings show that quantitative analysis of EEG maxpeak frequency is an easy and useful measure for differential dementia diagnosis. |
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Language
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English
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Source (journal)
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Journal of Alzheimer's disease. - -
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Publication
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2017
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ISSN
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1387-2877
1875-8908
[Electronic]
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DOI
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10.3233/JAD-160188
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Volume/pages
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55
:1
(2017)
, p. 53-58
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ISI
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000387671600004
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Pubmed ID
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27636837
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Full text (Publisher's DOI)
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Full text (open access)
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