Publication
Title
Lower blood pressure and apathy coincide in older persons with poorer functional ability : the discontinuation of antihypertensive treatment in elderly people (DANTE) study Leiden
Author
Abstract
ObjectivesTo examine the association between blood pressure (BP) measures and symptoms of apathy and depression in older adults with various levels of functional ability. DesignCross-sectional study using baseline data from the Discontinuation of Antihypertensive Treatment in Elderly people (DANTE) Study Leiden. SettingPrimary care setting, the Netherlands. ParticipantsCommunity-dwelling individuals aged 75 and older (N=430). MeasurementsSystolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were measured during home visits. Symptoms of apathy and depression were assessed using the Apathy Scale and the Geriatric Depression Scale (GDS-15), respectively. Stratified linear regression was performed in participants with better and worse functional ability according to the median of the Groningen Activity Restriction Scale. ResultsIn participants with lower functional ability, each 10-mmHg lower SBP, DBP, and MAP was associated with higher Apathy Scale scores (0.63, 0.92, and 0.94 points, respectively, all P<.005) but not with GDS-15 scores. In participants with higher functional ability, BP measures were not associated with Apathy Scale or GDS-15 scores. ConclusionIn older participants with poorer functional ability, lower BP was associated with more symptoms of apathy but not depression.
Language
English
Source (journal)
Journal of the American Geriatrics Society. - New York
Publication
New York : 2015
ISSN
0002-8614
DOI
10.1111/JGS.13199
Volume/pages
63 :1 (2015) , p. 112-117
ISI
000348374200015
Full text (Publisher's DOI)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
External links
Web of Science
Record
Identifier
Creation 17.11.2016
Last edited 01.02.2023
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