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Title
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Intramuscular adipose tissue and the functional components of sarcopenia in hospitalized geriatric patients
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Author
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Abstract
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| Intramuscular adipose tissue (IMAT) could be an important missing value in the assessment of sarcopenia. This study tries to determine the relation between IMAT, muscle strength, functionality and mortality. In addition, the relation with nutritional status is screened. For six months, all patients admitted to the University Geriatric Center of Antwerp were evaluated for strength (hand grip), functionality (short physical performance batterySPPB) and nutritional status. After one year, patients/relatives were contacted to obtain a current health status (mortality). A total of 303 patients were included at a mean age of 83.0 ± 6.4 years. The mean percentage of IMAT was 29.2% ± 13.0% (range 3.2%86.2%). There was a negative correlation between IMAT and both grip strength and SPPB. SPPB was positively correlated with both grip strength and muscle mass. There was a positive correlation between IMAT and mortality. There was a negative correlation between grip strength, SPPB and mortality. IMAT did not have a clear relation with nutritional status. IMAT should be addressed in the work-up of sarcopenia, as it is correlated with muscle strength, functionality and mortality. In this cohort of hospitalized geriatric patients, there is a mean of about one-third of measured muscle volume that appears to be adipose tissue. |
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Language
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English
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Source (journal)
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Geriatrics. - [S.l.]
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Publication
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[S.l.]
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MDPI AG
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2017
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ISSN
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2308-3417
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DOI
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10.3390/GERIATRICS2010011
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Volume/pages
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2
:1
(2017)
, p. 1-12
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Article Reference
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11
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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