Publication
Title
A systematic review and meta-regression analysis of mivacurium for tracheal intubation
Author
Abstract
We systematically reviewed factors associated with intubation conditions in randomised controlled trials of mivacurium, using random-effects meta-regression analysis. We included 29 studies of 1050 healthy participants. Four factors explained 72.9% of the variation in the probability of excellent intubation conditions: mivacurium dose, 24.4%; opioid use, 29.9%; time to intubation and age together, 18.6%. The odds ratio (95% CI) for excellent intubation was 3.14 (1.655.73) for doubling the mivacurium dose, 5.99 (2.1415.18) for adding opioids to the intubation sequence, and 6.55 (6.017.74) for increasing the delay between mivacurium injection and airway insertion from 1 to 2 min in subjects aged 25 years and 2.17 (2.012.69) for subjects aged 70 years, p < 0.001 for all. We conclude that good conditions for tracheal intubation are more likely by delaying laryngoscopy after injecting a higher dose of mivacurium with an opioid, particularly in older people.
Language
English
Source (journal)
Anaesthesia. - London
Publication
London : 2014
ISSN
0003-2409
DOI
10.1111/ANAE.12786
Volume/pages
69 :12 (2014) , p. 1377-1387
ISI
000345215400012
Note
3rd joint Statistical Meeting, organised by the Deutsche Arbeitsgemeinschaft Statistik (DAGStat), March 2013, Freiburg, Germany.
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UAntwerpen
Faculty/Department
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Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 02.03.2017
Last edited 01.12.2022
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