Title
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Influence of the incorporation of (s)-9-(3,4-dihydroxy-butyl)adenine on the enzymatic stability and base-pairing properties of oligodeoxynucleotides
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Author
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Abstract
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(S)-9-(3,4-dihydroxybutyl)adenine was used at several positions as nucleoside substitute in the synthesis of dimers and 13-mers. Therefore we used the phosporamidite and the H-phosphonate chemistry. The nuclease susceptibilities and the base-pairing properties of these oligomers have been evaluated. |
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Language
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English
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Source (journal)
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Nucleic acids research. - London
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Publication
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London
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1991
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ISSN
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0305-1048
1362-4962
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DOI
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10.1093/NAR/19.10.2587
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Volume/pages
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19
:10
(1991)
, p. 2587-2593
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ISI
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A1991FP31900005
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Full text (Publisher's DOI)
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