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Title
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Airborne allergic contact dermatitis caused by isothiazolinones in water-based paints : a retrospective study of 44 cases
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Author
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Institution/Organisation
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French Society of Dermatology
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Abstract
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| Background. Airborne allergic contact dermatitis caused by paints containing isothiazolinones has been recognized as a health hazard. Objectives. To collect epidemiological, clinical and patch test data on airborne allergic contact dermatitis caused by isothiazolinone-containing paints in France and Belgium. Methods. A descriptive, retrospective study was initiated by the Dermatology and Allergy Group of the French Society of Dermatology, including methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI)-and/or MI-sensitized patients who developed airborne allergic contact dermatitis following exposure to isothiazolinone-containing paint. Results. Forty-four cases were identified, with mostly non-occupational exposure (79.5%). Of the patients, 22.5% of also had mucosal symptoms. In several cases, the dermatitis required systemic corticosteroids (27.3%), hospitalization (9.1%), and/or sick leave (20.5%). A median delay of 5.5 weeks was necessary to enable patients to enter a freshly painted room without a flare-up of their dermatitis. Approximately one-fifth of the patients knew that they were allergic to MI and/or MCI/MI before the exposure to paints occurred. Conclusion. Our series confirms that airborne allergic contact dermatitis caused by paints containing isothiazolinones is not rare, and may be severe and long-lasting. Better regulation of isothiazolinone concentrations in paints, and their adequate labelling, is urgently needed. |
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Language
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English
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Source (journal)
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Contact dermatitis. - Copenhagen
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Publication
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Copenhagen
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2017
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ISSN
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0105-1873
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DOI
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10.1111/COD.12795
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Volume/pages
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77
:3
(2017)
, p. 163-170
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ISI
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000406785800005
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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