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Title
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Ventilation rate in adults with a tracheal tube during cardiopulmonary resuscitation : a systematic review
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Author
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Abstract
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| Aim: The optimal ventilation rate during cardiopulmonary resuscitation (CPR) with a tracheal tube is unknown. We evaluated whether in adults with cardiac arrest and a secure airway (tracheal tube), a ventilation rate of 10 min(-1), compared to any other rate during CPR, improves outcomes. Methods: A systematic review up to 14 July 2016. We included both adult human and animal studies. A GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach was used to evaluate the quality of evidence for each outcome. Results: We identified one human observational study with 67 patients and ten animal studies (234 pigs and 30 dogs). All studies carried a high risk of bias. All studies evaluated for return of spontaneous circulation (ROSC). Studies showed no improvement in ROSC with a ventilation rate of 10 min-1 compared to any other rate. The evidence for longer-term outcomes such as survival to discharge and survival with favourable neurological outcome was very limited. Conclusion: A ventilation rate recommendation of 10 min-1 during adult CPR with a tracheal tube and no pauses for chest compression is a very weak recommendation based on very low quality evidence. (C) 2017 Elsevier B.V. All rights reserved. |
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Language
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English
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Source (journal)
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Resuscitation. - Limerick, 1972, currens
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Publication
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Clare
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Elsevier ireland ltd
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2017
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ISSN
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0300-9572
[print]
1873-1570
[online]
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DOI
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10.1016/J.RESUSCITATION.2017.07.018
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Volume/pages
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119
(2017)
, p. 5-12
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ISI
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000408866700013
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Pubmed ID
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28739281
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Full text (Publisher's DOI)
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Full text (open access)
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Full text (publisher's version - intranet only)
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