A ternary supramolecular system containing a boronated DNA-metallointercalator, β-cyclodextrin and the hexanucleotide <script type="math/tex">d(GTCGAC)_{2}</script>

Ching, H.Y. Vincent; Buck, Damian P.; Bhadbhade, Mohan; Collins, J. Grant; Rendina, Louis M.

doi:10.1039/C1CC15552K

Title

A ternary supramolecular system containing a boronated DNA-metallointercalator, β-cyclodextrin and the hexanucleotide $d(GTCGAC)_{2}$

Author

Ching, H.Y. Vincent

Buck, Damian P.

Bhadbhade, Mohan

Collins, J. Grant

Rendina, Louis M.

Abstract

Solution NMR studies of the interaction between the hexanucleotide d(GTCGAC)2, β-cyclodextrin and a boronated 2,2′:6′,2′′-terpyridineplatinum(II) complex containing 1,12-dicarba-closo-dodecaborane(12) (1,12-closo-carborane) reveal the formation of a remarkable ternary supramolecular system in which the terpyridine ligand is intercalated between the C3 and G4 bases, whilst the closo-carborane moiety is encapsulated by the cyclic sugar.

Language

English

Source (journal)

Chemical communications / Royal Society of Chemistry [London] - London, 1996, currens

Publication

London : Royal Society of Chemistry , 2012

ISSN

1359-7345 [print]

1364-548X [online]

DOI

10.1039/C1CC15552K

Volume/pages