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Title
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Reduced interhemispheric coherence in dyslexic adults
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Author
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Abstract
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| Introduction Developmental dyslexia has been associated with reduced interhemispheric neural connectivity in children. The present study investigated functional interhemispheric connectivity in male dyslexic adults. Methods A group of 19 dyslexic men were compared to a group of 15 controls on interhemispheric coherence of the dominant frequency in the power spectrum during a visuo-spatial attention task. The coherence between a left hemisphere centralparietal electrode and the respective right hemisphere electrode and surrounding sites was analysed. Results Compared to controls, the dyslexic group demonstrated reduced, and more diffuse, interhemispheric coherence of alpha activity in the centralparietal cortex. No group differences in interhemispheric coherence were found on frontal, temporal or central sites. Conclusions The deviant pattern of functional connectivity in dyslexics is suggestive of an altered development of neural circuitry that may lead to deficits in magnocellular processing. |
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Language
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English
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Source (journal)
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Cortex. - Milano
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Publication
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Milano
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2010
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ISSN
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0010-9452
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DOI
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10.1016/J.CORTEX.2009.09.006
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Volume/pages
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46
:6
(2010)
, p. 794-798
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ISI
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000277780100010
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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