Publication
Title
Exosomes as diagnostic and predictive biomarkers in lung cancer
Author
Abstract
The concept of exosomes has evolved from be considered garbage bags to the demonstration that exosomes could play very interesting roles and functions, from biomarkers detection to the potential of work as drug delivery systems. It has been widely proved that exosomes can contain key molecules important for the tumour development. The current review summarizes the latest investigations developed in the field of predictive exosomal biomarkers. The microRNAs (miRNAs) are the more known molecules due to their amount inside the exosomes and the sensitivity of the techniques available for their study. However, exosomal proteins, RNA and DNA are becoming an interesting and more feasible field of study due to the improvement in the techniques available for their analysis. In the future years, it is hoped that exosomes will become an established member of the liquid biopsies in the clinical practice due to their diagnostic and prognostic properties.
Language
English
Source (journal)
Journal of thoracic disease / Guangzhou hu xi ji bing yan jiu suo; Hu xi ji bing guo jia zhong dian shi yan shi. - Hong Kong, 2009, currens
Publication
Shatin : Ame publ co , 2017
ISSN
2072-1439
DOI
10.21037/JTD.2017.10.67
Volume/pages
9 :s:[13] (2017) , p. S1373-S1382
ISI
000417755700007
Pubmed ID
29184676
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identifier
Creation 08.02.2018
Last edited 09.10.2023
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