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Title
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Molecular detection of airborne Emergomyces africanus, a thermally dimorphic fungal pathogen, in Cape Town, South Africa
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Author
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Abstract
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| Emergomyces africanus is a thermally dimorphic fungus that causes a systemic mycosis in immunocompromised persons in South Africa. Infection is presumed to follow inhalation of airborne propagules. We developed a quantitative PCR protocol able to detect as few as 5 Es. africanus propagules per day. Samples were collected in Cape Town, South Africa over 50 weeks by a Burkard spore trap with an alternate orifice. We detected Es. africanus in air samples from 34 days (10%) distributed over 11 weeks. These results suggest environmental exposure to airborne Es. africanus propagules occurs more commonly in endemic areas than previously appreciated. |
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Language
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English
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Source (journal)
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PLoS neglected tropical diseases
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Publication
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2018
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ISSN
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1935-2727
1935-2735
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DOI
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10.1371/JOURNAL.PNTD.0006174
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Volume/pages
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12
:1
(2018)
, 12 p.
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Article Reference
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e0006174
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ISI
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000424022700038
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Pubmed ID
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29357352
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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