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Tozasertib analogues as inhibitors of necroptotic cell death
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| Abstract |
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English
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Journal of medicinal chemistry. - Washington, D.C., 1963, currens | |
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Washington, D.C. : 2018
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0022-2623 [print]
1520-4804 [online]
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| Volume/pages |
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61:5(2018), p. 1895-1920
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| ISI |
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000427331500011
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| Pubmed ID |
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29437386
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| Project info |
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Identification, lead optimization and validation of necroptosis inhibitors. High-end molecular dynamics simulations combined with click chemistry synthesis to develop novel therapeutic compounds starting from small molecule fragments. Computational investigations of the catalytic mechanism of Staphylococcus aureus transglycosylase: design and chemical synthesis of novel mechanism-based inhibitors.
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Publications with a UAntwerp address
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| Creation |
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19.03.2018
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| Last edited |
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15.07.2020
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