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Title
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Onchocerciasis-associated epilepsy, an additional reason for strengthening onchocerciasis elimination programs
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Author
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Abstract
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| A high prevalence of epilepsy has been observed in onchocerciasis-endemic regions with high onchocerciasis transmission. Recent epidemiological studies suggest that Onchocerca volvulus infection is the trigger causing the seizures, which appear in previously healthy children between the ages of 3 and 18 years. Persons with onchocerciasis-associated epilepsy present with a wide spectrum of seizures, including atonic and myoclonic neck seizures; but also absences and most frequently generalized tonic-clonic seizures. Often individuals present with intellectual disabilities and psychiatric disorders and occasionally with 'Nakalanga' features such as severe stunting with delayed or absent external signs of sexual development. Onchocerciasis-associated epilepsy, because of its importance as a public health problem, is an additional reason for strengthening onchocerciasis elimination programs. |
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Language
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English
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Source (journal)
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Trends in parasitology. - London
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Publication
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Oxford
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Elsevier sci ltd
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2018
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ISSN
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1471-4922
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DOI
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10.1016/J.PT.2017.11.009
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Volume/pages
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34
:3
(2018)
, p. 208-216
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ISI
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000426213900007
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Pubmed ID
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29288080
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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