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Title
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Shared mechanisms among probiotic taxa : implications for general probiotic claims
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Author
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Abstract
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| Strain-specificity of probiotic effects has been a cornerstone principle of probiotic science for decades. Certainly, some important mechanisms are present in only a few probiotic strains. But scientific advances now reveal commonalities among members of certain taxonomic groups of probiotic microbes. Some clinical benefits likely derive from these shared mechanisms, suggesting that sub-species-specific, species specific or genus-specific probiotic effects exist. Human trials are necessary to confirm specific health benefits. However, a strain that has not been tested in human efficacy trials may meet the minimum definition of the term `probiotic' if it is a member of a well-studied probiotic species expressing underlying core mechanisms and it is delivered at an effective dose. |
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Language
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English
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Source (journal)
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Current opinion in biotechnology. - Chicago, Ill.
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Publication
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London
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Current biology ltd
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2018
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ISSN
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0958-1669
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DOI
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10.1016/J.COPBIO.2017.09.007
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Volume/pages
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49
(2018)
, p. 207-216
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ISI
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000426224300031
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Pubmed ID
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29128720
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Full text (Publisher's DOI)
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Full text (open access)
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