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Shared mechanisms among probiotic taxa : implications for general probiotic claims
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| Abstract |
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| Strain-specificity of probiotic effects has been a cornerstone principle of probiotic science for decades. Certainly, some important mechanisms are present in only a few probiotic strains. But scientific advances now reveal commonalities among members of certain taxonomic groups of probiotic microbes. Some clinical benefits likely derive from these shared mechanisms, suggesting that sub-species-specific, species specific or genus-specific probiotic effects exist. Human trials are necessary to confirm specific health benefits. However, a strain that has not been tested in human efficacy trials may meet the minimum definition of the term `probiotic' if it is a member of a well-studied probiotic species expressing underlying core mechanisms and it is delivered at an effective dose. |
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English
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Current opinion in biotechnology. - Chicago, Ill. | |
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London : Current biology ltd, 2018
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0958-1669
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49(2018), p. 207-216
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000426224300031
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29128720
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