Publication
Title
Lymphoblast-derived integration-free ISRM-CON9 iPS cell line from a 75 year old female
Author
Abstract
Human lymphoblast cells were used to generate integration-free induced pluripotent stem cells (iPSCs) employing episomal-based plasmids expressing OCT4, SOX2, NANOG, LIN28, c-MYC and L-MYC. The derived iPSCs were defined as pluripotent based on (i) expression of pluripotency-associated markers, (ii) embryoid body-based differentiation into cell types representative of the three germ layers and (iii) the similarity between the transcriptomes of the iPSC line and the human embryonic stem cell line H1 with a Pearson correlation of 0.95. (c) 2017 The Authors. Published by Elsevier B.V.
Language
English
Source (journal)
Stem cell research. - Place of publication unknown
Publication
Place of publication unknown : 2018
ISSN
1873-5061
1876-7753
Volume/pages
26(2018), p. 76-79
ISI
000425879600011
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Project info
VIB-Systems biology of pathways involving brain ageing (AgedBrainSYSBIO).
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 29.03.2018
Last edited 10.09.2021
To cite this reference