Publication
Title
Localized prostate cancer and robot-assisted laparoscopic radical prostatectomy: a retrospective, comparative study between pre- and post-operative Gleason scores
Author
Abstract
Introduction: To compare the pre- and post-operative Gleason scores (GS) in patients with localized prostate cancer treated with robot-assisted laparoscopic radical prostatectomy. Materials and methods: A single center, retrospective comparison between pre- and postoperative GS. Age, prostate volume, PSA, number of biopsies, number of positive cores, biopsy GS, cTNM, final pathology GS and pTNM of 286 patients were retrieved. They were divided into risk groups. Results: A total of 286 patients with a mean age at surgery of 64.64 +/- 7.81 y and mean PSA-value of 9.35 +/- 8.38 ng/mL. Mean prostate volume was 55.09 +/- 24.93 mL, mean number of biopsies was 11.90 +/- 4.63. Mean percentage of positive cores was 36.90 +/- 22.42%. A GS of <7 was seen in 23.4%, 66.8% had a GS of 7 and 9.7% of >7 in final pathology. Of the total, 38.1% were pre-operative low risk, 58.7% of them had an upgrade in GS on final pathology, 45.1% were in the intermediate risk group, 5.4% showed a downgrade, 64.3% remained stable and 30.2% had an upgrade in GS. Also, 16.8% were high risk patients of which 35.4% had a downgrade, 39.6% remained stable and 25% showed an upgrade of the GS. Conclusions: We found a substantial underestimation of the GS in the pre-operative setting when compared to the GS in final pathology.
Language
English
Source (journal)
Acta chirurgica Belgica. - Brussel, 1946 - 1996
Publication
Brussel : 2018
ISSN
0001-5458
Volume/pages
118 :1 (2018) , p. 15-20
ISI
000430091600003
Pubmed ID
28720050
Full text (Publisher's DOI)
UAntwerpen
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 04.05.2018
Last edited 20.09.2021
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