Publication
Title
Tackling poor specificity of cocaine color tests by electrochemical strategies
Author
Abstract
This paper presents electrochemical strategies for the fast screening of cocaine and most common cutting agents found in seized drug samples. First, a study on the performance of Scott color tests on cocaine and a wide range of cutting agents is described. The cutting agents causing false positive or false negative results when in mixture with cocaine are identified. To overcome the lack of specificity of color tests, we further propose a fast screening strategy by means of square wave voltammetry on disposable graphite screen printed electrodes, which reveals the unique fingerprint of cocaine and cutting agents. By employing a forward and backward scan and by a dual pH strategy, we enrich the electrochemical fingerprint and enable the simultaneous detection of cocaine and cutting agents. The effectiveness of the developed strategies was tested for the detection of cocaine in seized cocaine samples and compared with the color tests. Moreover, we prove the usefulness of square wave voltammetry for predicting possible interfering agents in color tests, based on the reduction peak of cobalt thiocyanate. The developed electrochemical strategies allow for a quick screening of seized cocaine samples resulting in a selective identification of drugs and cutting agents.
Language
English
Source (journal)
Analytical chemistry. - Washington, D.C., 1948, currens
Analytical chemistry. - Washington, D.C., 1948, currens
Publication
Washington, D.C. : 2018
ISSN
0003-2700 [print]
5206-882X [online]
Volume/pages
90 :11 (2018) , p. 6811-6819
ISI
000434893200066
Pubmed ID
29741867
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Project info
Novel electrochemical strategies for rapid, on-site multiscreening of illicit drugs (NARCOREADER).
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 29.05.2018
Last edited 20.09.2021
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