|
Title
|
|
|
|
Clinical predictors of residual sleep apnea after weight loss therapy in obese adolescents
|
|
|
Author
|
|
|
|
|
|
|
Abstract
|
|
|
|
| Objective To investigate clinical factors that could predict residual sleep-disordered breathing (SDB) after weight loss. Study design Obese subjects between 10 and 19 years of age were recruited while entering an in-patient weight loss treatment program. All subjects underwent anthropometry and sleep screening using a portable device at baseline and after 4-6 months of therapy. Sleep and International Study of Asthma and Allergies in Childhood questionnaires were completed at baseline. Results A total of 339 patients were included. Median age was 15.4 years (10.1-19.1). Body mass index z score at baseline was 2.75 ± 0.42, and 35% of subjects were boys. SDB was present in 32%. After a mean decrease in body mass index z score of 32%, residual SDB was found in 20% of subjects with SDB at baseline. Subjects with more severe SDB (OR 1.18; CI 1.01-1.34; P = .02) and respiratory allergies (OR 7.85; CI 1.20-51.39; P = .03) were at higher risk of developing residual SDB, unlike age, sex, and anthropometric variables. Conclusions Weight loss was successful for treating SDB in 80% of patients. More severe SDB and the presence of respiratory allergies at baseline were associated with a higher risk of residual SDB after weight loss. |
|
|
|
Language
|
|
|
|
English
|
|
|
Source (journal)
|
|
|
|
The journal of pediatrics. - St.Louis, Mo.
|
|
|
Publication
|
|
|
|
St.Louis, Mo.
:
2018
|
|
|
ISSN
|
|
|
|
0022-3476
|
|
|
DOI
|
|
|
|
10.1016/J.JPEDS.2017.12.056
|
|
|
Volume/pages
|
|
|
|
196
(2018)
, p. 189-+
|
|
|
ISI
|
|
|
|
000432452300035
|
|
|
Pubmed ID
|
|
|
|
29502877
|
|
|
Full text (Publisher's DOI)
|
|
|
|
|
|
|
Full text (open access)
|
|
|
|
|
|
|
Full text (publisher's version - intranet only)
|
|
|
|
|
|