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Title
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IgLoN5-associated encephalitis with atypical brain magnetic resonance imaging and cerebrospinal fluid changes
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Author
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Abstract
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| IgLON5-associated encephalitis is a syndrome with different clinical presentations consisting of sleep dysfunction, bulbar dysfunction, chorea, and progressive supranuclear palsy-like symptoms whereas dysautonomy and cognitive decline usually appear in later stages of the disease. We report a case of a patient with IgLON5-associated encephalitis presenting with rapidly progressive cognitive decline and atypical inflammatory lesions on brain magnetic resonance imaging, oligoclonal bands on cerebrospinal fluid, anti-IgLON5 antibodies exclusively of the IgG1 class, and a fierce inflammatory reaction on brain biopsy, who responded favorably to immunotherapy. |
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Language
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English
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Source (journal)
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Frontiers in neurology / Frontiers Research Foundation (Lausanne, Switzerland) - Lausanne, 2010, currens
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Publication
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Lausanne
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Frontiers Research Foundation
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2018
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ISSN
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1664-2295
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DOI
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10.3389/FNEUR.2018.00329
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Volume/pages
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9
(2018)
, 5 p.
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Article Reference
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329
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ISI
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000432402700001
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Pubmed ID
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29867738
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Medium
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E-only publicatie
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Full text (Publisher's DOI)
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Full text (open access)
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