Publication
Title
External factors affecting fertility, and how to correct their impact
Author
Abstract
Fertility of both men and women has been negatively influenced by external factors and life style in recent decennia. Mechanisms of hormone disruption, oxidative damage, and epigenetic DNA changes play a pivotal role in this process. In Belgium, strict regulations have been imposed to reduce the exposure to xeno-estrogens, which has resulted in a partial recovery of sperm quality. At the other hand, more couples require in vitro fertilisation (IVF) whereby ovarian stimulation may be associated with epigenetic DNA hyper-methylation of follicular cells, and increased risk of carcinogenesis among offspring. In order to reduce the health risks for the offspring it is recommended to optimize the oxidative, epigenetic and metabolic situation of both parents by means of lifestyle adaptation, and the use of appropriate food supplementation before conception and during pregnancy.
Language
English
Source (journal)
Facts, views & vision in obgyn : issues in obstetrics, gynaecology and reproductive health. - Place of publication unknown
Publication
Place of publication unknown : Flemish Society of Obstetrics, Gynaecology & Reproductive Health , 2017
ISSN
2032-0418
Volume/pages
9 :4 (2017) , p. 217-221
ISI
000434850800006
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 10.07.2018
Last edited 03.09.2021
To cite this reference