Title
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Evolution over time in the cost-effectiveness of pneumococcal conjugate vaccine (PCV13) in older Australians due to herd protection from infant vaccination
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Author
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Abstract
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In many settings, serotype changes as a result of infant 13-valent pneumococcal conjugate vaccine (PCV13) programs are likely to continue after the introduction of adult PCV13 programs. We applied a multi-cohort model to explore how potential serotype changes may impact on the cost-effectiveness of PCV13 use in Australian adults aged over 65 years. We found assumptions around continued herd protection from infant PCV13 programs to be critical when assessing the cost-effectiveness of adult PCV13 vaccination in Australia. Future cost-effectiveness analyses of adult PCV13 programs need to carefully consider how to predict these future changes in serotypes, with Australian data suggesting that the changes post-PCV13 use in infants may be different than post-PCV7. (C) 2018 Elsevier Ltd. All rights reserved. |
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Language
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English
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Source (journal)
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Vaccine / International Society for Vaccines. - Amsterdam
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Publication
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Amsterdam
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2018
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ISSN
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0264-410X
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DOI
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10.1016/J.VACCINE.2018.03.006
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Volume/pages
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36
:16
(2018)
, p. 2057-2060
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ISI
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000430525400001
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Full text (Publisher's DOI)
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Full text (publisher's version - intranet only)
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