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Title
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The six-item cognitive impairment test is associated with adverse outcomes in acutely hospitalized older patients : a prospective cohort study
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Author
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Abstract
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| Aim: The study aim was to investigate whether cognitive impairment, measured by the Six-Item Cognitive Impairment Test (6-CIT), is an independent predictor of adverse outcomes in acutely hospitalized older patients. Methods: This was a prospective multicenter study including acutely hospitalized patients aged 70 years and older. Multivariable logistic regression was used to investigate whether impaired cognition (6-CIT >= 11 points) was an independent predictor of 90-day adverse outcome, a composite measure of functional decline and mortality. Secondary endpoints were hospital length of stay, new institutionalization, and in-hospital mortality. Results: In total, 196 (15.6%) of 1,252 included patients had a 6-CIT >= 11. Median age was 80 years (interquartile range 74-85). Patients with impaired cognition had higher rates of 90-day adverse outcome (41.7% compared to 30.3% in 1,056 not cognitively impaired patients, p = 0.009). Impaired cognition was a predictor of 90-day adverse outcome with a crude odds ratio (OR) of 1.64 (95% CI 1.13-2.39), but statistical significance was lost when fully corrected for possible confounders (OR 1.44, 95% CI 0.98-2.11). For all secondary outcomes, impaired cognition was an independent predictor. Conclusions: In the acute hospital setting, the 6-CIT is associated with 90-day adverse outcome and is an independent predictor of hospital length of stay, new institutionalization, and in-hospital mortality. (C) 2018 The Author(s) Published by S. Karger AG, Basel |
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Language
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English
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Source (journal)
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Dementia and geriatric cognitive disorders extra. - Basel, 2011, currens
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Publication
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Basel
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Karger
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2018
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ISSN
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1664-5464
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DOI
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10.1159/000490240
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Volume/pages
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8
:2
(2018)
, p. 259-267
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ISI
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000444639500007
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Pubmed ID
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30140275
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Full text (Publisher's DOI)
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Full text (open access)
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