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Title
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NADPH oxidases : new players in TNIF-induced necrotic cell death
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Author
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Abstract
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| Necrosis is a caspase-independent cell death process involving the generation of reactive oxygen species (ROS). In a recent issue of Molecular Cell, Kim et al. (2007) reported on a novel TNF receptor 1 necrotic signaling complex inducing TRADD- and RIP1-dependent recruitment and activation of the ROS-generating Nox1 NADPH oxidase complex. |
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Language
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English
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Source (journal)
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Molecular cell. - Cambridge, Mass.
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Publication
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Cambridge, Mass.
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2007
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ISSN
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1097-2765
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DOI
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10.1016/J.MOLCEL.2007.06.002
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Volume/pages
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26
:6
(2007)
, p. 769-771
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ISI
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000247639600001
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Full text (Publisher's DOI)
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