Publication
Title
Caspases leave the beaten track : caspase-mediated activation of NF-κB
Author
Abstract
The proteolytic activity of the cysteinyl aspartate-specific proteases, named caspases, mainly connotes their central role in apoptosis and inflammation. In this review we report on recent data on the role of caspases in the activation of nuclear factor kB (NF-kB), a transcription factor that fulfils a central role in innate and adaptive immunity, in cellular stress responses and in the induction of antiapoptotic factors. Two different mechanisms by which caspases activate the NF-kB pathway are discussed.
Language
English
Source (journal)
The journal of cell biology / American Society for Cell Biology. - New York
Publication
New York : 2006
ISSN
0021-9525
Volume/pages
173:2(2006), p. 165-171
ISI
000237055500007
Full text (Publisher's DOI)
UAntwerpen
Publication type
Subject
External links
Web of Science
Record
Identification
Creation 18.10.2018
Last edited 29.07.2021