Publication
Title
The Maudsley Staging Method as predictor of electroconvulsive therapy effectiveness in depression
Author
Abstract
Objective Method To investigate the potential role of the Maudsley Staging Method (MSM) in the prediction of electroconvulsive therapy (ECT) outcome in severely depressed adults. Between August 2015 and August 2017, 73 consecutive patients with a major depressive episode (DSM-IV-TR) scheduled for ECT were recruited. Prior to their first ECT session, the MSM was completed to assess the level of therapy resistance. To determine the reduction in depression severity and response and remission rates, symptom severity was assessed at baseline and within one week after the last ECT session using the 17-item Hamilton Depression Rating Scale (HDRS17). Results Conclusion The percentage of symptom reduction following ECT was best predicted by the MSM episode duration and depression severity factors (R-2 completer sample 0.24). Episode duration alone was the best predictor of remission (area under the ROC curve for completers: 0.72). Adding age to the models increased their predictive capacity. An adapted version of the MSM gauging shorter episode duration, more severe depressive symptoms and older age is significantly associated with ECT effectiveness in adults with severe recurrent depression and is thus highly suitable for use in clinical practice, promoting the shared treatment decision-making process.
Language
English
Source (journal)
Acta psychiatrica Scandinavica. - Copenhagen
Publication
Copenhagen : 2018
ISSN
0001-690X
Volume/pages
138 :6 (2018) , p. 605-614
ISI
000449521200012
Pubmed ID
30270433
Full text (Publisher's DOI)
Full text (publisher's version - intranet only)
UAntwerpen
Faculty/Department
Research group
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 10.12.2018
Last edited 15.11.2021
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