Publication
Title
UPLC/MS MS data of testosterone metabolites in human and zebrafish liver microsomes and whole zebrafish larval microsomes
Author
Abstract
This article represents data regarding a study published in Toxicology in vitro entitled "in vitro CYP-mediated drug metabolism in the zebrafish (embryo) using human reference compounds" (Saad et al., 2017) [1]. Data were acquired with ultra-performance liquid chromatography - accurate mass mass spectrometry (UPLC-amMS). A full spectrum scan was conducted for the testosterone (TST) metabolites from the microsomal stability assay in zebrafish and humans. The microsomal proteins were extracted from adult zebrafish male (MLM) and female (FLM) livers, whole body homogenates of 96 h post fertilization larvae (EM) and a pool of human liver microsomes from 50 donors (HLM). Data are expressed as the abundance from the extracted ion chromatogram of the metabolites. (C) 2017 The Authors. Published by Elsevier Inc.
Language
English
Source (journal)
Data in Brief
Publication
Amsterdam : Elsevier science bv , 2018
ISSN
2352-3409
Volume/pages
16 (2018) , p. 644-648
ISI
000449758500087
Pubmed ID
29541660
Full text (Publisher's DOI)
Full text (open access)
UAntwerpen
Faculty/Department
Research group
Project info
Development of an integrated strategy to characterize new lead compounds based on natural pro-drugs and their metabolites.
Publication type
Subject
Affiliation
Publications with a UAntwerp address
External links
Web of Science
Record
Identification
Creation 10.12.2018
Last edited 26.09.2021
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